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Evolution Finds Shelter in Small Spaces

Description: 
When RNA is replicated in cell-free systems, a ubiquitous problem is the hijacking of the system by short parasitic RNA sequences. In this issue of Chemistry & Biology, Bansho et al. show that compartmentalization into water-in-oil droplets can ameliorate this problem, but only if the droplets are small. This result helps to both recapitulate abiogenesis and optimize synthetic biology. Refers to: Bansho, Yohsuke, et al. "Importance of Parasite RNA Species Repression for Prolonged Translation-Coupled RNA Self-Replication." Chemistry & Biology 19.4 (2012): 478-487.
Record Format: 
application/pdf
Record Date: 
2012-04-01T07:00:00Z
Publisher: 
PDXScholar
Subject: 
RNA -- Biology
RNA -- Evolution
Evolutionary genetics
Biochemistry, Biophysics, and Structural Biology
Type: 
text
Raw Url: 
https://pdxscholar.library.pdx.edu/do/oai/?metadataPrefix=&verb=GetRecord&identifier=oai:pdxscholar.library.pdx.edu:chem_fac-1045
Source: 
Chemistry Faculty Publications and Presentations
Repository Record Id: 
oai:pdxscholar.library.pdx.edu:chem_fac-1045
SetSpec: 
publication:clas
publication:communities
publication:chem_fac
publication:chem
Record Title: 
Evolution Finds Shelter in Small Spaces
Identifier: 
https://pdxscholar.library.pdx.edu/chem_fac/45
https://pdxscholar.library.pdx.edu/cgi/viewcontent.cgi?article=1045&context=chem_fac
Author: 
Lehman, Niles
Database: 
Resource OE Format: