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  1. Impact of HIV on CD8+ T Cell CD57 Expression Is Distinct from That of CMV and Aging

    Background: Chronic antigenic stimulation by cytomegalovirus (CMV) is thought to increase ‘‘immunosenesence’’ of aging, characterized by accumulation of terminally differentiated CD28- CD8+ T cells and...

  2. Dynamic Modeling of Nonmedical Opioid Initiation: Epidemic and Access

    We report development of a systems level dynamic model of initiation and nonmedical use of pharmaceutical opioids in the US. The model calibrated to 1995-2005 National Survey of Drug Use and Health (NSDUH)...

  3. Process Evaluation and Assessment of Use of a Large Scale Water Filter and Cookstove Program in Rwanda

    Background: In an effort to reduce the disease burden in rural Rwanda, decrease poverty associated with expenditures for fuel, and minimize the environmental impact on forests and greenhouse gases from...

  4. State Experiences with Affordable Housing Plus Services: Report to Seniors and Persons with Disabilities, On The Move

    Housing developers, providers, policy makers, and advocates, increasingly recognize that for some groups of individuals, access to affordable housing alone is "not enough." That is, some individuals require...

  5. Thirdhand Tobacco Smoke: Emerging Evidence and Arguments for a Multidisciplinary Research Agenda

    There is broad consensus regarding the health impact of tobacco use and secondhand smoke exposure, yet considerable ambiguity exists about the nature and consequences of thirdhand smoke (THS). We introduce...

  6. Patient-Guided Investigation of the Restoration of Health Following Traumatic Brain Injury

    The development of emergency department medical interventions and the implementation of fast-transport trauma systems has decreased the rate of death resulting from traumatic brain injury (TBI). Without...

  7. The Meanings in the Messages: How SMS Reminders and Real-time Adherence Monitoring Improve Antiretroviral Therapy Adherence...

    To understand how a pilot intervention combining SMS reminders with real-time adherence monitoring improved adherence to HIV antiretroviral therapy (ART) for adults initiating treatment in rural Uganda.

  8. Multiple Measures Reveal Antiretroviral Adherence Successes and Challenges in HIV-Infected Ugandan Children

    Background: Adherence to HIV antiretroviral therapy (ART) among children in developing settings is poorly understood.

  9. Sexual Relationships Outside Primary Partnerships and Abstinence are Associated with Lower Adherence and Adherence Gaps: Data...

    Objective—To assess the role of sexual relationships on levels and patterns of adherence to medication for pre-exposure prophylaxis (PrEP) against HIV.

  10. A Community-Based Wellness Program to Reduce Depression in African Americans: Results From a Pilot Intervention

    Background African-Americans are less likely than non-Hispanic Whites to find antidepressants acceptable or seek care for depression. Objective To develop and pilot-test a culturally-tailored, community-based,...

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